Role of Omega-3 Polyunsaturated Fatty Acid Supplementation in Patients with Type 2 Diabetes Mellitus

Document Type : Mini review


1 Clinical Pharmacy & Pharmacy Practice, Faculty of Pharmacy, Damanhour University, Damanhour 22514, Egypt.

2 Ministry of Health and Population, Damanhour City, Egypt.

3 Internal Medicine and Diabetes Department, Damanhour Medical National Institute, Damanhour City, Egypt

4 Department of Pharmacology and Toxicology, Faculty of Pharmacy, Damanhour University, Damanhour, Egypt. Department of Pharmacology and Toxicology, College of Pharmacy, Arab Academy for Science, Technology and Maritime Transport, Alexandria, Egypt.


Background and Aim: The advantages of Omega-3 fatty acid, which is one of the polyunsaturated fatty acids (PUFA), for health are the subject of an increasing number of studies. Omega-3 may help prevent or treat obesity and related metabolic illnesses, according to studies conducted both on mice and people. This study aims at exploring the benefits of Omega-3 in type 2 diabetes mellites.
Method: Online databases PubMed, Google Scholar and Science Direct were searched for articles discussing Omega-3 fatty acid and diabetic patients in the recent five years (2017-2023).
Results: Recent researches, have shown the value of omega-3 fatty acid supplements, such as docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA), in the treatment of a several disorders. Omega-3 fatty acids have beneficial effects on glycemic control and insulin resistance in patients with type 2 diabetes mellites.
Conclusions: Clinical studies have demonstrated that omega-3 fatty acids may assist in controlling type 2 diabetes mellites, reducing obesity and related metabolic diseases.


Main Subjects